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Position Statements

Use and Misuse of Androgens

Table 1 - Use, Misuse and Abuse of Androgens

USE Physiological
(androgen deficiency) Classical androgen deficiency ("hypogonadism")

Age-related partial androgen deficiency

  • micropenis (neonatal)
  • delayed puberty
  • *aged men
*Androgen deficiency secondary to chronic disease

Induced androgen deficiency

  • *hormonal male contraception
Pharmacological osteoporosis
(non-androgen deficiency) anemia due to marrow or renal failure
advanced breast cancer
excessively tall stature in boys
  postmenopausal vaginal atrophy (dermal application)
MISUSE Inappropriate indications In absence of proven androgen deficiency
male infertility
sexual dysfunction/impotence
"male menopause", "andropause"
older aged men (>65 years of age)
  non-specific symptoms
ABUSE Absence of medical indication
Sporting competitive power sports (athletics, weight-lifting, football, swimming, rowing, boxing)
Recreational body-building
Cosmetic "body beautiful" subculture
Occupational security, police, armed forces, professional sports

* indications that remain to be fully evaluated by controlled clinical trials for safety and efficacy

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Revised January 2001